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Project ID/Title:07-02. Direct Protein/Cell Lithography on Membranes
Advisor:Chia-Chi Ho
Academic Title:Associate Professor
Department:Chemical & Materials Engineering
Department Website:www.eng.uc.edu/dept_cme
Email:cho@alpha.che.uc.edu
Phone:513-556-2438
Fax:513-556-3473
Graduate Program(s):Chemical Engineering
Co-Advisor(s):Carlos Co, Assistant Professor of Chemical Engineering
Project Description:Functional tissues consist of mixtures of endothelial cells, which form blood vessels necessary for transporting oxygen and nutrients, with a second cell type, e.g., liver, or cardiovascular cells. Yet biocompatible membranes for tissue engineering have largely been limited to directing the structure of individual cell types due to the lack of membrane design and manufacturing technologies that offer control on the spatial organization of multiple cell types. Here we propose a novel approach based on a protein/cell photo resist that allows for the formation of complementary patterns of different cell types or protein arrays on biodegradable membranes.