University of Cincinnati Home Page.
University of Cincinnati logo.
Project ID/Title:07-04. Computational Simulation of a Natural Olfactory Biosensor
Advisor:Steven Kleene
Academic Title:Professor
Department:Cell and Cancer Biology
Department Website:http://cna.uc.edu/
Email:Steve@syrano.acb.uc.edu
Phone:513-558-6099
Fax:513-558-2727
Graduate Program(s):Neuroscience Mathematical Sciences
Co-Advisor(s):Donald French, Department of Mathematical Sciences
Project Description:Olfactory receptor neurons detect environmental odors with great sensitivity. However, it is not known how the structural and dynamic properties of their sensory endings contribute to this sensitivity. Our research group combines expertise in computational neuroscience and electrophysiology to model the electrical properties of the sensory endings. In particular, we are modeling how the locations and interactions of the two types of membrane channel optimize the sensitivity of the biosensor.